Soft-tissue sarcomas (STS) are a group of rare, heterogeneous, and aggressive tumors, with high metastatic risk and relatively few efficient systemic therapies.In the quest for new treatments, the immune system represents an attractive therapeutic target.Recently, PD1/PDL1 inhibitors showed very promising results in patients with solid tumors.PDL1
Geminiviruses are known to exhibit both prokaryotic and eukaryotic features in their genomes, with the ability to express their genes and even replicate in bacterial cells.We have demonstrated previously the existence of Massage Oil unit-length single-stranded circular DNAs of Ageratum yellow vein virus (AYVV, a species in the genus Begomovirus, fa
Nasogastric (NG) tubes are commonly used for enteral feeding.Complications of feeding tube misplacement include malnutrition, pulmonary aspiration, and even death.We built a Bayesian network (BN) to analyse the risks associated with available bedside tests to verify tube position.Evidence on test validity (sensitivity and specificity) ErgoRapido Ha